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Prostate cancer

ICD-10 C61

¹ per 100,000 persons, age-standardised according to the old European standard population

* calculated using the period method for 2015 / 2016

Age-standardised incidence rate¹95.9
Age-standardised mortality rate¹18.8
5-year prevalence250,700
10-year prevalence466,100
Relative 5-year survival rate*89 %
Relative 10-year survival rate*88 %

The number of new cases of prostate cancer diagnosed in 2017 was around 62,230. After an increase over nearly two decades, the age-standardised incidence rate remained largely constant after 2003 and then declined substantially between 2011 and 2016. A similar development can be observed in many other western industrialized nations and is probably due to prostate specific antigen (PSA) testing as a screening test: a long initial period of increasing use followed by a recent decline.

Age-standardised incidence and mortality rates, ICD-10 C61, Germany 1999 – 2016/2017, projection (incidence) through 2020, per 100,000 (old European standard population). Source: © German Centre for Cancer Registry Data at the Robert Koch Institute Age-standardised incidence and mortality rates, ICD-10 C61, Germany 1999 – 2016/2017, projection (incidence) through 2020, per 100,000 (old European standard population)

In contrast to the incidence rate, the age-standardised mortality rate decreased continuously until 2007 and has remained fairly stable since then. Current incidence in Germany is similar to rates in other central European countries.

Prostate cancer rarely occurs before the age of 50: For a 35-year-old man, the risk of falling ill in the next 10 years is less than 0.1 percent, whereas that of a 75-year-old man is about 5 percent. The overall relative 5-year survival rate for prostate cancer is 89 percent. About two thirds of tumours are diagnosed at an early stage (UICC I/II).

Risk factors and early detection

The causes of prostate cancer and the factors influencing its course remain largely unknown. Age is an important risk factor. Men of black African origin develop prostate cancer more frequently than Europeans and white North Americans, while Asians are less often affected. Incidence of the disease among close relatives is a well-established risk factor. In addition, chronic inflammation of the prostate and sexually transmitted diseases appear to increase the risk of prostate cancer.

There is little evidence of lifestyle- or environment-related risk factors. However, maintaining a normal weight and getting sufficient exercise may reduce the risk of prostate cancer.

For men from the age of 45 years, the statutory early detection programme in Germany currently provides an annual check-up, the examination of the external genital organs and the palpation of the prostate and lymph nodes. PSA testing is not part of the statutory early detection program, as the net benefit of population-wide PSA screening has not yet been demonstrated beyond doubt.

Date: 22.04.2021

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